The DisGeNET Cytoscape App is designed to visualize, query and analyse a network representation of the gene, and variant-disease associations in DisGeNET. The DisGeNET Cytoscape App uses the current version (7.0) of the DisGeNET data. In the App, gene-disease networks, variant-disease networks, disease-disease networks, and gene-gene networks can be generated.
The App assists the user in the interpretation and exploration of human complex diseases with respect to their genetic origin by a variety of built-in functions. Using the DisGeNET Cytoscape App you can perform queries restricted to
(i) the original data source
(ii) the association type
(iii) the disorder class of interest
(iv) a range of score
(v) a range of evidence index
(vi) an evidence level
(vii) specific diseases, genes, or variants, or combinations of them
(viii) lists of diseases, genes, or variants, or combinations of them
The app also allows: <p>
1. Colouring nodes by disease class <p>
2. Accessing the data via REST <p>
3. Annotating DisGeNET gene projections with diseases <p>
4. Expanding node information by data source <p>
5. Easy annotation of external protein, and variant networks with diseases <p>
