CARLSBAD (Confederated Annotated Research Libraries of Small molecule BioActivity Data) Cytoscape plugin for visualization and exploration of chemical pattern bioactivity networks. The CARLSBAD plugin allows researchers to generate hypotheses involving the relationships between biological targets, chemical compounds and their common chemical patterns (CCPs).
CARLSBAD is a database and knowledge inference system that integrates multiple bioactivity datasets in order to provide researchers with novel capabilities for the mining and exploration of available structure activity relationships (SAR) throughout chemical biology space. The powerful cheminformatics and pattern recognition algorithms combined with network analysis methodology allow researchers using CARLSBAD to generate hypotheses involving the relationships between biological targets, chemical compounds and their common chemical patterns (CCPs). The CARLBAD platform consists of a web-based extraction tool called SNAKE and a network analysis plugin for Cytoscape called CARLSBAD. In addition, the use of Cytoscape enables researchers to infer novel associations via the powerful biological network visualization environment that Cytoscape provides.
